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Orion IVF Pune

Best ICSI Center in Pune

Intracytoplasmic sperm injection (ICSI) — which first appeared as an add-on to in vitro fertilization (IVF) for couples experiencing acute male infertility — is now used in minor or even inexplicable male infertility. Male sperm can sometimes be unable to penetrate the egg’s outer layer. According to the American Society for Reproductive Medicine, ICSI is a safe and effective treatment for couples suffering from male factor infertility, and it will increase the chances of fertilization for couples who had poor fertilization in a previous IVF cycle.

Since the technique’s introduction in the early 1990s, the use of ICSI for couples with male factor infertility has expanded. However, ICSI is steadily being used in women that do not have male factor infertility, even though the treatment has not been proven to increase clinical outcomes.

In April 1989, the first infant born from gamete micromanipulation (a procedure in which special instruments and inverted microscopes are used to assist embryologists in choosing and picking an individual sperm for ICSI IVF) was a Singaporean. Gianpiero Palermo developed the methodology at the Vrije Universiteit Brussel’s Center for Reproductive Medicine — which is led by Paul Devroey and Andre Van Steirteghem. The discovery was made by accident. The operation was first carried out in 1987, but only to the pronuclear stage. The first powered embryo was produced by ICSI in 1990, but the first complete ICSI birth occurred on January 14, 1992, after an April 1991 conception. ICSI’s success has successfully shifted emphasis away from determining what induces male infertility and toward the female, optimizing the provision of eggs and a receptive endometrium, in which ICSI’s success is dependent.

ICSI is performed as part of IVF. Since ICSI is performed in the hospital, the IVF procedure would seem to be no different from an IVF treatment without ICSI. ICSI (intracytoplasmic sperm injection) is a technique performed in the laboratory by embryologists who prepare the sperm and inject it into a mature egg. This treatment necessitates cutting-edge technology and the most qualified embryologists, both of which are readily available at Orion IVF, one of the best IVF centers in Pimpri-Chinchwad, Pune.

ICSI Procedure

ICSI is usually done after a transvaginal oocyte extraction procedure to extract one or more oocytes from a woman. To determine if ICSI will help you get pregnant, the fertility team considers all aspects of your fertility. Your embryologist will track the development of the embryo after an egg has been fertilized using ICSI. The healthiest embryos are selected for transplant or may be preserved for potential use. The procedure of ICSI is described below:

ICSI Cycle Preparation 

For a female partner – Fertility medications are used to activate the ovaries so that a few eggs mature. When eggs are found by ultrasound, they need to be surgically removed. The number of eggs produced by a woman can vary based on a variety of factors, including her age and diagnosis. Eggs are stored in an incubator after they have been retrieved.

For a male partner – Semen samples are obtained from a male partner following 3 to 5 days of sexual abstinence. Depending on a man’s diagnosis, sperm can be extracted by stimulation (the most common method) on the day of an egg retrieval operation on a female partner or before the day. Following that, the sperm is isolated, and unnecessary biological material is removed from the sample.

Extraction of Sperm 

Once the sperm samples are collected — the embryologists analyze and extract a single sperm — a very delicate, sharp, and hollow needle is used. The most fertile sperm cell is used for egg implantation.

Fertilization –

The needle is then delicately embedded into the eggshell and the cytoplasm. After that, the egg is cultured in a hatchery, where it is continually checked for fertilization.

Embryo Transfer –

The fetus exchange procedure is utilized to physically embed the developing life within the woman’s uterus after the ICSI steps are completed and preparation is fruitful.

Post Transfer –

At that point, it’s fair a case of keeping an eye out for early pregnancy signs. A blood test or ultrasound may be used by the fertility specialist to assess whether or not implantation and conception have occurred.

Who should consider ICSI?

Typically, IVF candidates whose sperm contributor has sperm quality or output problems should expect ICSI. Among them are the following scenarios:

  • The sperm has low motility, or the capacity to pass effectively across the female reproductive tract or medium in an IVF operation.
  • The sperm is misshaped or unable to bind to the egg.
  • Few sperm are generated for IVF, or a blockage prevents the sperm from leaving the man’s reproductive tract, necessitating a surgical operation to extract the sperm.
Success Rate

ICSI fertilizes 50 to 80 percent of the eggs. You might think that ICSI-IVF fertilizes all embryos, but this is not the case. Fertilization is not guaranteed except after sperm is inserted into the embryo. Keep in mind that fertilization rates do not indicate clinical pregnancy or live birth rates. Vasectomy reversal is one of the applications for sperm injection. However, possible factors that can affect pregnancy rates (and live birth rates) in ICSI include the degree of DNA fragmentation assessed, for example, by the comet assay, advanced maternal age, and sperm content.

ICSI, along with IVF, is one of the most often used methods of Assisted Reproductive Technology. Since its inception, it has resulted in the birth of many thousands of babies around the world that may not have been born otherwise. Although success rates may give you an idea of the chances of conceiving, they are not tailored to your particular circumstance. Your fertility doctor will be able to give you an idea of your chances of success with ICSI. When compared to the national average, our ICSI success rates are excellent. When compared to the national average, our ICSI success rates are exceptional. Success rates vary depending on age, health, and the cause of infertility. Our success rates are attributed to the specialist care provided by our staff, Orion Hospital constant surveillance, and experienced fertility healthcare practitioners.

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